KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
9.39
Human Site:
T179
Identified Species:
14.76
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
T179
K
K
E
H
I
P
G
T
L
R
F
R
L
S
P
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
T179
K
K
E
H
I
P
G
T
L
R
F
R
L
S
P
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
G148
V
E
I
P
K
D
V
G
P
P
P
P
V
S
K
Dog
Lupus familis
XP_533153
501
54075
K179
K
K
E
H
I
L
G
K
L
Q
F
R
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
T179
A
R
K
E
H
K
G
T
A
R
F
R
L
S
P
Rat
Rattus norvegicus
P08461
632
67147
P309
T
S
L
K
P
Q
A
P
P
P
V
P
P
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
F178
H
Q
P
G
K
L
Q
F
R
L
S
P
A
A
R
Frog
Xenopus laevis
NP_001087423
478
50485
R164
L
R
M
S
P
A
A
R
H
I
I
D
T
H
G
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
S172
A
A
P
P
T
A
G
S
A
P
P
A
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
V278
P
T
A
P
P
V
G
V
P
A
P
S
V
A
T
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
S191
E
P
A
K
P
A
A
S
S
Q
P
S
P
P
A
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
Q166
E
G
V
S
E
S
A
Q
F
S
D
M
R
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
K276
I
L
I
P
E
G
S
K
D
V
A
V
G
K
P
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
A169
A
K
K
S
D
V
A
A
P
Q
G
R
I
F
A
Red Bread Mold
Neurospora crassa
P20285
458
48601
E160
P
T
P
A
P
E
P
E
N
T
S
F
T
G
R
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
6.6
80
N.A.
53.3
0
N.A.
N.A.
0
0
13.3
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
100
20
86.6
N.A.
66.6
0
N.A.
N.A.
13.3
6.6
20
N.A.
N.A.
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
7
14
7
0
20
34
7
14
7
7
7
7
14
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
7
0
0
7
0
7
7
0
0
0
% D
% Glu:
14
7
20
7
14
7
0
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
7
0
27
7
0
7
0
% F
% Gly:
0
7
0
7
0
7
40
7
0
0
7
0
7
7
7
% G
% His:
7
0
0
20
7
0
0
0
7
0
0
0
0
14
0
% H
% Ile:
7
0
14
0
20
0
0
0
0
7
7
0
7
0
0
% I
% Lys:
20
27
14
14
14
7
0
14
0
0
0
0
0
7
7
% K
% Leu:
7
7
7
0
0
14
0
0
20
7
0
0
34
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
14
7
20
27
34
14
7
7
27
20
27
20
14
14
34
% P
% Gln:
0
7
0
0
0
7
7
7
0
20
0
0
0
0
7
% Q
% Arg:
0
14
0
0
0
0
0
7
7
20
0
34
7
7
14
% R
% Ser:
0
7
0
20
0
7
7
14
7
7
14
14
0
34
0
% S
% Thr:
7
14
0
0
7
0
0
20
0
7
0
0
14
0
7
% T
% Val:
7
0
7
0
0
14
7
7
0
7
7
7
14
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _